NR3C1 and cancer: In addition, we observed that NR3C1 knockdown reinforced Bax expression and impaired Bcl-2 expression in cancer cells, while miR-1270 inhibitor reintroduction attenuated Bax expression that was reinforced by NR3C1 knockdown and recovered Bcl-2 expression that was impaired by NR3C1 knockdown (Fig. 7C).