DNMT3A and Miyoshi myopathy: Study findings indicated that DNMT3A mutations were present in newly diagnosed MM patients and those treated by autologous stem cell transplantation (ASCT).141,142 Furthermore, DNMT3A overexpression was demonstrated in the cells of MM patients.58,143 Different from lymphoma, studies showed that DNMT3A underexpression was associated with worse OS in MM patients.144