On the other hand, aberrant occupation of BRD4 inhibited c-fos transcription, which in turn inhibited epithelial differentiation.369 A similar oncogenic translocation to NUT was also discovered in BRD3.370,371 The evidence of histone acetylation readers contributing to hematologic malignancies are lacking and requires further investigation. The gene discussed is BRD4; the disease is hematologic disorder.