The NSD2/FGFR3 translocation was significantly related to 13q- and worse prognoses, which could not be overcome even by a high-dose regimen and ASCT.408,409NSD3 was also found to fuse to NUP98, caused by the t(8;11)(p11.2;p15) translocation, in AML and radiation-related MDS patients.410,411. Here, NUP98 is linked to acute myeloid leukemia.