Circ0006168, a cyclic RNA having a complementary miR-194-5p binding sequence with KDM3C, can positively regulate the expression of KDM3C, and its downregulation can inhibit the growth of tumors and enhance the sensitivity of cells to paclitaxel by decreasing the expression of KDM3C (Table 4).290 In conclusion, the KDM family is an important regulator of tumor resistance. Here, JMJD1C is linked to neoplasm.