AURKA and breast carcinoma: In order to evaluate whether TPX2 co-overexpression has functional consequences on processes described to be dependent on nuclear AurkA, we generated additional cell lines for the expression of AURKA, or AURKA/TPX2, in MCF10A breast non-transformed epithelial cells (Fig 5), based on the ongoing active investigation of the nuclear role of AurkA in breast cancer (see the Introduction section).