IL10 and campylobacteriosis: 126 This was shown by Mansfield et al., who successfully developed a murine campylobacteriosis model, in which the absence of IL-10 drastically increases the LOS sensitivity of mice and impairs the immune system’s capacity to resolve inflammation.127 However, this work was done in mice that overexpressed innate immune receptors.126 Finally, the SAB IL-10-deficient mice were confirmed to reproducibly develop typical symptoms of acute campylobacteriosis upon C. jejuni infection.