To examine the effects of the METTL14/miR‐6769b‐3p and METTL14/miR‐499a‐3p axis on glycolysis in vitro and in vivo, we verified that stable miR‐6769b‐3p and miR‐499a‐3p overexpression inhibited tumor growth, and miR‐6769b‐3p and miR‐499a‐3p up‐regulation antagonized the tumor growth‐promoting effect caused by METTL14 knockdown in vivo (Figs EV5E and F, and 5I–K). This evidence concerns the gene METTL14 and neoplasm.