To investigate the clinical significance of METTL14, glycolytic components (SLC2A3 and PGAM1), and microRNAs (miR‐6769b‐3p and miR‐499a‐3p) in CRC patients, IHC, ISH, and real‐time PCR analysis showed that the levels of SLC2A3 and PGAM1 were higher in CRC tissues than those in normal tissues, while the levels of miR‐6769b‐3p and miR‐499a‐3p were higher in adjacently normal tissues (Appendix Fig S5A–D). This evidence concerns the gene METTL14 and colorectal carcinoma.