Moreover, we observed that METTL14 was inversely correlated with poor histological differentiation, AJCC III/IV stage, and tumor size (≥ 30 cm3) in p53‐WT CRC patients (Fig 6H), while no significant relationship was found between METTL14 and clinicopathological features of CRC patients with p53 mutations (Appendix Fig S9A). The gene discussed is METTL14; the disease is colorectal carcinoma.