Mettl14 knockdown in tumor‐associated macrophages in tumor microenvironment triggers CD8+ T cells differentiating toward a dysfunctional state in mouse models, thus impairing their ability to eliminate tumors, highlighting the tumor‐suppressive role of Mettl14 in tumor microenvironment (Dong et al, 2021). The gene discussed is CD8A; the disease is neoplasm.