Five of these 16 proteins were previously reported in AKI-related studies (Havcr1/KIM1, AGT, UMOD, β2M, Clu), 6 were supported by evidence (Fgg, Fgb, Fga, Alb, Gc, Hp), and 5 were new candidate proteins not previously associated with AKI (Serpina1, Apoa1, F2, Plg, Hrg). The gene discussed is APOA1; the disease is acute kidney injury.