HLA-DRB1 and myeloid sarcoma: Another study, which analyzed DNA methylation in monocytes from MS patients, confirmed the methylation at the HLA-DRB1 locus and demonstrated that homozygous DRB1*15:01 patients showed significantly lower levels of methylation at the HLA-DRB1 locus than heterozygous patients and non-carriers (Kular et al., 2018).