The following issues are outside the scope of the clinical guideline: people with other types of diabetes or at high risk of developing T2DM; women with T2DM who are pregnant, planning a pregnancy, or breastfeeding; management of T2DM using western medicines or insulin; and detailed recommendations on the management of comorbidities, emergencies, and complications related to T2DM. The gene discussed is INS; the disease is type 2 diabetes mellitus.