CKS1-knockdown in NQO1-expressing cancer cells resulted in an increased proportion of cells at G2/M phase relative to transfection with siCont (Figure 3F,G, middle panel), whereas overexpression of CKS1 decreased the proportion of cells at G2/M phase compared to NQO1-deficient RKO/pshNQO1 and MDA-MB-231/pCont cells (Figure 3F,G, middle panel). This evidence concerns the gene NQO1 and cancer.