PTP4A1 and hydrops fetalis: Along with the increased lipid accumulation, deficiency of PTP4A1 in hepatocytes of mice fed an HF diet lessened the levels of GLUT2 on the plasma membrane (Figure 2C and S4F) and the uptake of 2-(N-(7-Nitrobenz-2-oxa-1,3-diazol-4-yl)Amino)-2-Deoxyglucose (2-NBDG), a fluorescent glucose analog (Figure 2D).