MKI67 and neoplasm: H&E staining for tumor formation and Ki67 staining for the degree of proliferation demonstrated that cells expressing phosphomimetic β-cateninmtGSK3β (S311D of β-cateninmtGSK3β) increased tumorigenesis and cell proliferation in metastatic nodules, while S311A in β-cateninmtGSK3β did not affect tumorigenesis and cell proliferation (Figure 5C-F).