ITGAX and neoplasm: Consistent with this result, the flow cytometry analysis further showed that the frequency of tumor-infiltrating IL-12p70+CD11c+ cells was significantly increased in mice receiving the chitosan-SRA siRNA compared to those treated with chitosan-scramble siRNA (Figure 6E), suggesting enhanced T cell-mediated antitumor immunity by targeted SRA inhibition involves improved functionality of DCs in vivo.