To analyze whether IFI6 is induced after the infection with respiratory viruses, such as influenza and coronaviruses, lung adenocarcinoma-derived A549 and A549 cells overexpressing the SARS-CoV-2 receptor hACE-2, were infected with IAV (MOI 3) or SARS-CoV-2 (MOI 1), respectively. The gene discussed is IFI6; the disease is lung adenocarcinoma.