After the analysis of univariate Cox regression, a total of 15 prognosis-related genes of NSCLC were selected from an expression matrix of 1,006 cancer samples, such as ANO6, FPR2, PDGFB, TRIM58, CD300E, CXCL3, HLA-DMA, CTSM, ANOS1, NR3C2, BMP5, TLR7, FCGRT, LIFR, and PTGDR2. The gene discussed is PTGDR2; the disease is cancer.