Figure 1B showed that the expression levels of RBM15, FTO, YTHDC1, YTHDC2, HNRNPC, HNRNPA2B1, LRPPRC, IGF2BP1, IGF2BP2, IGF2BP3 were significantly correlated with the overall survival of patients with HNSCC (P<0.05) through Kaplan-Meier curve and log-rank test analysis. This evidence concerns the gene IGF2BP1 and head and neck squamous cell carcinoma.