PKMYT1 and breast cancer: Multiple omics data also confirmed that The DNA methylation level of PKMYT1 in breast cancer was lower than that in matched normal tissues (Figure 1D, p < 0.0001), and the mRNA level of PKMYT1 was positively correlated with the copy number variation (CNV) level of PKMYT1 (Figure 1E, p < 0.0001), while negatively correlated with methylation level (Figure 1F, p < 0.0001), indicating the potential association of PKMYT1 transcriptome level with genome level.