PLOD1 and polycystic ovary syndrome: For instance, FSH/LH ratio inversion is a characteristic of polycystic ovary syndrome with increased LH concentrations (14), while a high basal FSH/LH ratio is predictive of higher rates of cycle cancellation, poorer ovarian response to COS or lower pregnancy rates, even with different cutoff values (2, 3, and 3.6) in different studies (10–13).