The result of multivariate analysis showed that lnc-MyD88 [Hazard Ratio (HR) = 2.020, 95% CI = 1.217–3.351, P= 0.007], HGB (HR = 1.062, 95% CI = 1.008–1.120, P = 0.025), and ALT (HR = 1.041, 95% CI = 1.005–1.078, P = 0.025) had potential to distinguish HCC patients from healthy subjects (Figure 2C). This evidence concerns the gene MYD88 and hepatocellular carcinoma.