A preoperative assessment should be completed considering a full range of factors, such as advanced age, fracture site, thrombosis risk assessment [40], albumin level, anaemia, heart disease, respiratory disease, history of stroke, smoking, BMI, Parkinson’s disease and osteoporosis, to prevent, control and manage risk factors, adopt a similar treatment model and thinking to that of treating elderly hip fractures and establish a fast-track system. The gene discussed is ALB; the disease is anemia (phenotype).