ICAM1 and ocular cicatricial pemphigoid: Thus, it is likely that a combination of all of these estrogen-induced intercellular reactions, as well as the form of progesterone in OCP, influences gene expression and increases the development of inflammatory proteins, which in the case of our study is seen as an increased ICAM-1, TNF-α and MCP-1fold expression after treatment with OCP's, despite the lack of much larger fold expression.