The results showed that these molecules were associated with multiple individual tumours, and 11 of the related genes, including RAF1, EGFR, TP53, ERBB2, HSP90AA1, NOS3, CDK4, VEGFB, FLT1, STK11, and CDC37, were enriched in the PI3K-Akt signalling pathway [20, 21]. The gene discussed is CDK4; the disease is neoplasm.