Then, the infiltration proportions of 22 types of immune cells in all 342 GC patients are summarized in Fig. 5A. Moreover, totally 11 types of immune cells, including B cells naïve, T cells CD4 memory activated, T cells follicular helper, NK cells resting, Monocytes, Macrophages M0, Macrophages M1, Macrophage M2, Mast cells resting, Mast cells activated, and Neutrophils, showed significant infiltrating differences between high- and low-risk GC groups (Fig. 5B-L). This evidence concerns the gene CD4 and gastric cancer.