COL2A1 and osteoarthritis: Note that a previous study showed that Nfatc1 deletion in Col2a1-expressing cells (Nfatc1Col2a1 mice) does not affect articular cartilage integration or osteoarthritis progression induced by destabilization of the medial meniscus Greenblatt et al., 2013, suggesting that NFATc1 is dispensable in Col2a1-expressing differentiated articular chondrocytes.