RANBP1 and 22q11.2 deletion syndrome: For example, Ranbp1 heterozygotes do not display multiple phenotypes observed in Lgdel mice, including functional deficiencies in suckling, feeding and swallowing (16,17), including the significant delay in postnatal weight gain seen in LgDel pups that mirrors that observed in human infants with 22q11DS (16, Supplementary Material, Fig. S6).