Moreover, patients with ALBI grade 2/3 had higher baseline total bilirubin (p < 0.001), protein induced by vitamin K absence or antagonist‐II (PIVKA‐II) (p = 0.006), and maximum tumor diameter (p < 0.001), and lower albumin (p < 0.001) than patients with ALBI grade 1. This evidence concerns the gene ALB and neoplasm.