HGF and chronic pancreatitis: Inflammatory mediators in the tumor microenvironment increase the HGF gene expression in stromal cells.21 It was determined that the expression of HGF and c-MET in the tissue increased significantly during the development of experimental chronic pancreatitis.22 Studies detecting high HGF levels in the blood in acute and chronic pancreatitis after hepatopancreatic surgery are among the studies evaluating the relationship of HGF with inflammation.23-25