Similarly, low plasma PLP levels predispose to a higher risk of venous thrombosis(53), myocardial infarction(54), diabetes mellitus(55), COVID-19 infection(56), oxidative stress(38), increasing risk of cancer in diabetic patients(57,58), immune system disruption and CRP level elevations(39) that suggests increased risk of inflammation conditions(58). This evidence concerns the gene CRP and diabetes mellitus.