In both pancreatic cancer cell lines, cell viability, DNA synthesis capacity, and cell invasion were markedly decreased by DSCR9 overexpression but increased by miR-21-5p overexpression; the effects of DSCR9 overexpression on pancreatic cancer phenotype were significantly reversed by miR-21-5p overexpression (Figure 6A‒C). Here, DSCR9 is linked to pancreatic neoplasm.