In the pSS group, univariate analyses showed that food allergy (P = 0.02), AR/AC (P = 0.054), high levels of eosinophils (P < 0.01), high levels of immunoglobulins (P = 0.02), and positivity for anti-SSA antibody (P = 0.056) were risk factors for drug allergy (Fig. 1). This evidence concerns the gene TRIM21 and peeling skin syndrome.