Notably, when the MDA5+DM patients were divided into Alive and Dead groups, the frequency of both GZMK+GZMB− CD4 and GZMK+GZMB−CD8 T cells was significantly higher in the Dead group than in the Alive group (Dead vs. Alive: 1.8 ± 0.7% vs. 0.8 ± 0.7%; 2.4 ± 1.3% vs. 1.2 ± 0.85%, respectively) (Figure 4B). Here, IFIH1 is linked to dermatomyositis.