Glycan traits were integrated across glycan classes, i.e., N-, O-, and GSL-glycans, by summing up their values throughout the three classes in order to observe the impact of specific GSTs on the global glycomic phenotype of AML blasts (Additional file 2: Tables S1, S2, S3, S4, and S5). The gene discussed is HPGDS; the disease is acute myeloid leukemia.