INS and metabolic disease: As seen in animal experiments, the use of curcumin can lead to a decrease in insulin resistance (one of the key features of PCOS phenotype), a decrease in blood’s inflammatory factors such as CRP and IL-6 [18] (which are high in people with PCOS and have a direct relationship with insulin sensitivity [19], a decrease in FBS and cholesterol levels in people with metabolic disorders (complications of PCOS) [20], but the administration of curcumin can lead to improvement in insulin sensitivity, cholesterol levels and metabolic factors in people with PCOS as well.