Metabolic disorders are seen in women with PCOS include resistance to insulin, hyperinsulinemia, and dyslipidemia (decrease in High Density Lipoprotein- cholesterol (HDL-C), increase in total cholesterol, Low Density Lipoprotein- cholesterol (LDL-C), and triglycerides), so we can say that women with PCOS are prone to type 2 diabetes and cardiovascular diseases [10]. This evidence concerns the gene INS and metabolic disease.