As seen in animal experiments, the use of curcumin can lead to a decrease in insulin resistance (one of the key features of PCOS phenotype), a decrease in blood’s inflammatory factors such as CRP and IL-6 [18] (which are high in people with PCOS and have a direct relationship with insulin sensitivity [19], a decrease in FBS and cholesterol levels in people with metabolic disorders (complications of PCOS) [20], but the administration of curcumin can lead to improvement in insulin sensitivity, cholesterol levels and metabolic factors in people with PCOS as well. This evidence concerns the gene IL6 and polycystic ovary syndrome.