Kinase substrate enrichment analysis (KSEA)28 of GC-associated phospho-sites identified multiple kinases, including CDK1, CDK2, CSNK2A1, CAMK2A, PAK1, MAPK1, and MAPK3, were activated in GC tumor tissues (Fig. 1e). The gene discussed is CSNK2A1; the disease is gastric cancer.