BRD7 and neoplasm: In our previous study, we investigated the chromatin binding sites of BRD7 and its downstream regulatory network by using ChIP-sequencing and digital gene expression profiling (DGE), and the results revealed that BIRC2 is a potential target gene of BRD7 and mediates the regulation of the cell cycle and apoptosis-related pathways [22], these findings might support a potential transcriptional regulation mechanism by which BRD7 functions as a tumor suppressor in NPC.