CD8A and neoplasm: Figure 7 shows that BUB1/3 mRNA expression was not related to tumor purity. However, BUB1 mRNA expression was significantly correlated with B cells, neutrophils, CD4+T cells, and CD8+T cells (Figure 7A) BUB3 mRNA expression was significantly correlated with CD8+ T cells, B cells, and neutrophils (Figure 7B).