Finally, we investigated the role of c-Maf in podocytes and immune cells in DKD and the immunological consequences of c-Maf deficiency (46, 47) by staining macrophages expressing c-Maf and WT1 in kidney podocytes on STZ(12w) TAM(8w) and examining the expression of Il-10 and Il-17 genes on TAM(10d) and STZ(12w) TAM(8w). This evidence concerns the gene IL17A and diabetic kidney disease.