SLC47A1 and type 2 diabetes mellitus: In this regard, due to the high prevalence of T2DM on the one hand and its possible relationship with the variants of the SLC47A1 gene with the use of metformin, on the other hand, we decided to assess the association of rs2250486 and rs67238751 intronic variants in the SLC47A1 gene with response to metformin for the first time in the Iranian population with T2DM.