It has been shown that AD‐MSC‐derived exosomes promote ECs angiogenic capacity under OGD by miR‐181b‐mediated TRPM7 downregulation, leading to increased HIF‐1α expression and decreased expression of tissue inhibitor of metalloproteinase‐3 (TIMP‐3) expression.78 Here, HIF1A is linked to Alzheimer disease.