Surprisingly, the lysine content of the mRNAs whose translation was CDKAL1‐dependent was not significantly different (AAA codon) from or less (AAG codon) than that of CDKAL1‐independent mRNAs (Figure 4D), suggesting that the mechanism by which CDKAL1 maintains cancer cell stemness is independent of the known function of CDKAL1. The gene discussed is CDKAL1; the disease is cancer.