Our top results from the combined differential expression analysis identified several highly significant genes including Aspartate-beta-hydroxylase (ASPH), C5orf30, Diacylglycerol kinase (DGKH), and SLC26A6. The ASPH and C5orf30 gene products, which were identified as highly significant DEGs in our study, have been identified previously as markers of severe infection [58]. Here, MACIR is linked to infection.