PHB2 and breast cancer: LacRNA and PHB2 expression was much higher in three luminal type breast cancer lines with low metastatic potential (MCF7, T47D, and BT-474) than in five highly metastatic HER2-enriched and triple-negative breast cancer cell lines (SK-BR-3, MDA-MB-468, BT-549, MDA-MB-231, and LM2) (Fig. 5a).