CSC with self‐renewing capacity is thought to be essential for tumor initiation.[11] We next evaluated the effect of USP29 on the enrichment and activity of CSCs in vivo, limiting dilution assay (4 × 105, 4 × 104, or 1 × 104 cells) of MDA‐MB‐231 cells stably expressing control or USP29 shRNA were subcutaneously injected into nude mice. The gene discussed is USP29; the disease is neoplasm.