Gene set enrichment analysis (GSEA) highlighted several non-neuronal cell fate signatures among the upregulated genes, and indicated an overall enrichment of genes implicated in epilepsy, schizophrenia, and ASD among the deregulated genes in Myt1l-mutant brains [48, 49] (Supplementary Fig. S4D, E). Here, MYT1L is linked to schizophrenia.