The CRC patients’ risk scores were calculated as follows: (0.971881 × expression [ENO3]) + (0.385271 × expression [SERPINE1]) + (0.267247 × expression [TKTL1]) − (0.61523 × expression [HK1]) − (0.23354 × expression [ALDOB]) − (0.45796 × expression [GPI]). This evidence concerns the gene ENO3 and colorectal carcinoma.