Distinct clinical features may aid in the diagnosis of certain ataxias such as loss of taste sensation in mGluR1 ataxia and episodic ataxia which can arise in the context of contactin-associated protein-like 2 (CASPR2) autoimmunity (sometimes accompanying thymoma) [52, 53]. The gene discussed is CNTNAP2; the disease is Familial paroxysmal ataxia.