In literature, RAI3 has been suggested as prognostic marker in several cancer types, including colon cancer (Kume et al. 2014; Zougman et al. 2013), gastric cancer (Cheng et al. 2012), oral squamous cell carcinoma (Liu et al. 2013), and hepatocellular carcinoma (Zheng et al. 2014). This evidence concerns the gene GPRC5A and oral cavity squamous cell carcinoma.