NAPB and genetic developmental and epileptic encephalopathy: On the other hand, mutations in the NAPB gene [N-ethylmaleimide-sensitive factor (NSF)-attachment protein beta, OMIM *611270] that encodes for the SNAP-beta, a protein component of the SNARE (SNAP-receptor) complex, have been described in association with early-onset epileptic encephalopathy (EOEE) characterizing the multifocal intractable seizures in disorders of neurodevelopmental nature [10–13].