The colocalized SNP between PerioLT and T2D, rs17522122, maps to the 3’-UTR of AKAP6. The A-kinase anchor proteins are a group of proteins highly expressed in various brain regions, cardiac and skeletal muscle and tongue, with biological functions involved in anchoring protein kinase A to the nuclear membrane or sarcoplasmic reticulum. The gene discussed is AKAP6; the disease is type 2 diabetes mellitus.