HLA loci were more frequent in T1D patients compared to controls: DRB1*03, DRB1*1301, DQA1*0301, DQB1*0201. The DRB1*15 (43% vs 0) and DQA1*01 (79% vs 0) frequency were higher in healthy controls compared to the T1D patients. This evidence concerns the gene HLA-DRB1 and type 1 diabetes mellitus.