***The data actually shows that islet cell autoantibody positivity rates were as high in T1D patients as in the age-matched controls. This is suggestive of a systematic error (Quality control issues) and illustrates the importance of control population data for defining test specificity.***IAA was measured insulin treated diabetes of up to 1 year duration:insulin treatment may result in false positive results. This evidence concerns the gene INS and type 1 diabetes mellitus.